“The U.S. government’s policy of drug prohibition, like alcohol prohibition before it, is a failure. The economic analysis of fighting a supply-side drug war predicts that the war will enhance drug suppliers’ revenues, enabling them to continuously ratchet up their efforts to supply drugs in response to greater enforcement. The result is a drug war that escalates in cost and violence. The drug war causes drugs to be more potent and their quality less predictable than if drugs were legal, leaving the remaining users at greater risk and, in the face of higher prices, more likely to commit crimes to support their habit.”
http://www.econlib.org/library/Columns/y2013/Powelldrugs.html